Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPPYP00000001110annotation not available (66 aa)    
Predicted Functional Partners:
VASP
Vasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.
   
 0.753
CFL1
CFL1 isoform 4; Belongs to the actin-binding proteins ADF family.
   
 0.681
EVL
Ena/VASP-like protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization (By similarity).
   
 0.605
ENAH
ENAH isoform 1.
   
 0.600
ACTG2
ACTG2 isoform 3.
   
 0.585
CFL2
CFL2 isoform 1; Belongs to the actin-binding proteins ADF family.
   
 0.572
CDC42
Cell division cycle 42.
   
 0.558
DAAM1
Dishevelled associated activator of morphogenesis 1.
    
 0.541
DAAM2
Dishevelled associated activator of morphogenesis 2.
    
 0.541
WASL
WASL isoform 1.
    
 
 0.526
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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