| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGXT | AGXT2 | ENSPPYP00000014927 | ENSPPYP00000017192 | Serine--pyruvate aminotransferase. | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.818 |
| AGXT | CAT | ENSPPYP00000014927 | ENSPPYP00000024526 | Serine--pyruvate aminotransferase. | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | 0.648 |
| AGXT | GRHPR | ENSPPYP00000014927 | ENSPPYP00000021363 | Serine--pyruvate aminotransferase. | GRHPR isoform 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.958 |
| AGXT | HAO1 | ENSPPYP00000014927 | ENSPPYP00000011960 | Serine--pyruvate aminotransferase. | HAO1 isoform 1. | 0.800 |
| AGXT | HAO2 | ENSPPYP00000014927 | ENSPPYP00000001125 | Serine--pyruvate aminotransferase. | HAO2 isoform 1. | 0.813 |
| AGXT | HOGA1 | ENSPPYP00000014927 | ENSPPYP00000023748 | Serine--pyruvate aminotransferase. | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1. | 0.785 |
| AGXT | PEX12 | ENSPPYP00000014927 | ENSPPYP00000009205 | Serine--pyruvate aminotransferase. | Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. | 0.775 |
| AGXT | PIPOX | ENSPPYP00000014927 | ENSPPYP00000009127 | Serine--pyruvate aminotransferase. | PIPOX isoform 6. | 0.768 |
| AGXT | TYSND1 | ENSPPYP00000014927 | ENSPPYP00000002756 | Serine--pyruvate aminotransferase. | TYSND1 isoform 1. | 0.685 |
| AGXT2 | AGXT | ENSPPYP00000017192 | ENSPPYP00000014927 | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Serine--pyruvate aminotransferase. | 0.818 |
| AGXT2 | GRHPR | ENSPPYP00000017192 | ENSPPYP00000021363 | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | GRHPR isoform 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.928 |
| AGXT2 | HAO1 | ENSPPYP00000017192 | ENSPPYP00000011960 | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | HAO1 isoform 1. | 0.928 |
| AGXT2 | HAO2 | ENSPPYP00000017192 | ENSPPYP00000001125 | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | HAO2 isoform 1. | 0.938 |
| AGXT2 | HOGA1 | ENSPPYP00000017192 | ENSPPYP00000023748 | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1. | 0.910 |
| AGXT2 | PIPOX | ENSPPYP00000017192 | ENSPPYP00000009127 | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | PIPOX isoform 6. | 0.936 |
| CAT | AGXT | ENSPPYP00000024526 | ENSPPYP00000014927 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | Serine--pyruvate aminotransferase. | 0.648 |
| CAT | HAO1 | ENSPPYP00000024526 | ENSPPYP00000011960 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | HAO1 isoform 1. | 0.955 |
| CAT | HAO2 | ENSPPYP00000024526 | ENSPPYP00000001125 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | HAO2 isoform 1. | 0.955 |
| CAT | PEX12 | ENSPPYP00000024526 | ENSPPYP00000009205 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. | 0.640 |
| CAT | PIPOX | ENSPPYP00000024526 | ENSPPYP00000009127 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | PIPOX isoform 6. | 0.436 |
