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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPAG17SPAG17 isoform 2. (2223 aa)    
Predicted Functional Partners:
LRGUK
LRGUK isoform 1.
   
 
 0.761
SPAG6
Sperm associated antigen 6.
    
 
 0.748
CFAP221
CFAP221 isoform 2.
    
 
 0.664
RPTN
RPTN isoform 1.
    
 
 0.634
EFCAB6
EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.
   
 
 0.617
DNAI1
DNAI1 isoform 1.
   
  
 0.612
DPY30
Dpy-30 histone methyltransferase complex regulatory subunit.
    
 
 0.582
TEKT3
TEKT3 isoform 1.
   
  
 0.576
CR201_G0000772
DNAH10 isoform 10.
   
  
 0.564
DNAH10
DNAH10 isoform 1.
   
  
 0.564
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.