Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MAN1A2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (641 aa)    
Predicted Functional Partners:
MAN1B1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
0.930
MGAT1
MGAT1 isoform 12.
    
 0.928
MAN1C1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
  
  
 
0.919
MAN1A1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
  
  
 
0.919
SPPL3
SPPL3 isoform 1.
      
 0.731
ST3GAL4
ST3GAL4 isoform 10; Belongs to the glycosyltransferase 29 family.
      
 0.727
MAN2A1
Alpha-mannosidase.
   
 
 0.717
ST6GALNAC2
ST6GALNAC2 isoform 1; Belongs to the glycosyltransferase 29 family.
      
 0.658
MAN2A2
Alpha-mannosidase.
   
 
 0.652
TMTC3
TMTC3 isoform 1.
   
  
 0.645
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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