Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIM45TRIM45 isoform 4. (580 aa)    
Predicted Functional Partners:
ZNF227
Zinc finger protein 227.
   
 0.741
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 
 0.692
STAC
SH3 and cysteine rich domain.
    
 
 0.638
SORBS1
SORBS1 isoform 10.
    
 
 0.631
FCHSD2
FCH and double SH3 domains 2.
    
 
 0.631
SPART
SPART isoform 1.
      
 0.630
TRAT1
T cell receptor associated transmembrane adaptor 1.
      
 0.591
TRIM41
TRIM41 isoform 2.
      
 0.568
KNOP1
KNOP1 isoform 2.
    
 
 0.541
UBE2D1
Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.531
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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