Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CD2CD2 isoform 1. (351 aa)    
Predicted Functional Partners:
CD58
CD58 isoform 1.
    
 0.999
CR201_G0049459
CD8A isoform 1.
   
  
 0.953
CD3E
CD3E isoform 2.
   
 
 0.951
CD2BP2
CD2BP2 isoform 1.
    
 
 0.949
CD2AP
CD2 associated protein.
    
 
 0.939
CD3D
CD3D isoform 1.
   
 0.933
CD247
CD247 isoform 2.
   
 
 0.922
CD3G
CD3G isoform 1.
   
 
 0.915
ITK
Tyrosine-protein kinase.
   
 0.896
GZMA
GZMA isoform 1; Belongs to the peptidase S1 family.
   
 0.881
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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