Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGSF3IGSF3 isoform 2. (1227 aa)    
Predicted Functional Partners:
CDR2
Cerebellar degeneration related protein 2.
    
   0.672
RABGEF1
RABGEF1 isoform 2.
    
 0.663
GGT5
GGT5 isoform 2.
      
 0.648
CEACAM1
CEACAM1 isoform 2.
    
 0.641
GDAP2
GDAP2 isoform 1.
     
 0.585
PDZRN3
PDZ domain containing ring finger 3.
    
 
 0.569
MYLK
MYLK isoform 5.
    
 0.554
TNFRSF10B
TNFRSF10B isoform 3.
      
 0.554
TTC12
TTC12 isoform 5.
    
 
 0.535
CSF2RB
CSF2RB isoform 1.
      
 0.528
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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