Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CD58CD58 isoform 1. (250 aa)    
Predicted Functional Partners:
CD2
CD2 isoform 1.
    
 0.999
TNFSF15
TNFSF15 isoform 1.
      
 0.692
SAMSN1
SAMSN1 isoform 1.
   
 
 0.660
GPC3
GPC3 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
      
 0.658
SPG21
Maspardin; May play a role as a negative regulatory factor in CD4- dependent T-cell activation.
      
 0.656
LGALS9
Galectin.
    
 0.630
CD80
CD80 isoform 4.
      
 0.523
CD48
CD48 isoform 1.
   
  
 0.514
LTF
LTF isoform 1; Belongs to the transferrin family.
      
 0.501
TF
TF isoform 1; Belongs to the transferrin family.
      
 0.501
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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