ATP1A1 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ATP1A1

ATP1A1 isoform 7. (1003 aa)

Predicted Functional Partners:

ENSPPYP00000011229

0.994

ATP1A2

0.982

ATP1B1

0.969

ATP1A4

0.951

LOC103891919

0.927

ATP1B3

0.910

NDRG1

0.815

ATP4A

0.802

ATP4B

0.797

ATP12A

0.773

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP12A	ATP1A1	ENSPPYP00000005939	ENSPPYP00000001146	Sodium/potassium-transporting ATPase subunit alpha.	ATP1A1 isoform 7.	0.773
ATP12A	ATP1A2	ENSPPYP00000005939	ENSPPYP00000000749	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	0.899
ATP12A	ATP1A4	ENSPPYP00000005939	ENSPPYP00000000748	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.949
ATP12A	ATP1B1	ENSPPYP00000005939	ENSPPYP00000000625	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity).	0.875
ATP12A	ATP1B3	ENSPPYP00000005939	ENSPPYP00000015848	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.689
ATP12A	ATP4A	ENSPPYP00000005939	ENSPPYP00000011049	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.993
ATP12A	ATP4B	ENSPPYP00000005939	ENSPPYP00000006303	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.999
ATP12A	ENSPPYP00000011229	ENSPPYP00000005939	ENSPPYP00000011229	Sodium/potassium-transporting ATPase subunit alpha.	annotation not available	0.954
ATP12A	LOC103891919	ENSPPYP00000005939	ENSPPYP00000004488	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit gamma isoform X1.	0.668
ATP1A1	ATP12A	ENSPPYP00000001146	ENSPPYP00000005939	ATP1A1 isoform 7.	Sodium/potassium-transporting ATPase subunit alpha.	0.773
ATP1A1	ATP1A2	ENSPPYP00000001146	ENSPPYP00000000749	ATP1A1 isoform 7.	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	0.982
ATP1A1	ATP1A4	ENSPPYP00000001146	ENSPPYP00000000748	ATP1A1 isoform 7.	Sodium/potassium-transporting ATPase subunit alpha.	0.951
ATP1A1	ATP1B1	ENSPPYP00000001146	ENSPPYP00000000625	ATP1A1 isoform 7.	Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity).	0.969
ATP1A1	ATP1B3	ENSPPYP00000001146	ENSPPYP00000015848	ATP1A1 isoform 7.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.910
ATP1A1	ATP4A	ENSPPYP00000001146	ENSPPYP00000011049	ATP1A1 isoform 7.	Sodium/potassium-transporting ATPase subunit alpha.	0.802
ATP1A1	ATP4B	ENSPPYP00000001146	ENSPPYP00000006303	ATP1A1 isoform 7.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.797
ATP1A1	ENSPPYP00000011229	ENSPPYP00000001146	ENSPPYP00000011229	ATP1A1 isoform 7.	annotation not available	0.994
ATP1A1	LOC103891919	ENSPPYP00000001146	ENSPPYP00000004488	ATP1A1 isoform 7.	Sodium/potassium-transporting ATPase subunit gamma isoform X1.	0.927
ATP1A1	NDRG1	ENSPPYP00000001146	ENSPPYP00000021200	ATP1A1 isoform 7.	NDRG1 isoform 2.	0.815
ATP1A2	ATP12A	ENSPPYP00000000749	ENSPPYP00000005939	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	Sodium/potassium-transporting ATPase subunit alpha.	0.899