Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SYCP1Synaptonemal complex protein 1. (976 aa)    
Predicted Functional Partners:
SYCE1
SYCE1 isoform 4.
    
 0.965
SYCE2
Synaptonemal complex central element protein 2.
    
 0.958
SYCP3
Synaptonemal complex protein 3.
    
 0.945
DCAF12L1
DDB1 and CUL4 associated factor 12 like 1.
   
    0.831
ZFP2
ZFP2 zinc finger protein.
   
  0.829
HORMAD2
HORMAD2 isoform 1.
   
  
 0.746
PKM
Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (By similarity). Stimulates POU5F1-mediated transcriptional activation (By similarity). Promotes in a STAT1-dependent manner, the expression of the immune checkpoint protein CD274 in ARNTL/BMAL1-deficient macrophages (By similarity).
    
   0.736
REC8
REC8 meiotic recombination protein.
    
 0.724
CR201_G0049238
ZNF71 isoform 2.
   
  0.705
APITD1
CENPS isoform 1.
    
 0.696
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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