DENND2C protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DENND2C

DENND2C isoform 3. (661 aa)

Predicted Functional Partners:

RAB9B

0.765

C3orf67

0.718

RHOBTB3

0.629

RAB35

0.528

IFT27

0.528

AVL9

0.514

SYTL1

0.486

NRROS

0.485

CHM

0.449

CR201_G0031594

0.409

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AVL9	DENND2C	ENSPPYP00000019795	ENSPPYP00000001167	Late secretory pathway protein AVL9 homolog; Functions in cell migration; Belongs to the AVL9 family.	DENND2C isoform 3.	0.514
AVL9	RAB35	ENSPPYP00000019795	ENSPPYP00000005723	Late secretory pathway protein AVL9 homolog; Functions in cell migration; Belongs to the AVL9 family.	RAB35, member RAS oncogene family.	0.509
C3orf67	DENND2C	ENSPPYP00000015387	ENSPPYP00000001167	C3orf67 isoform 1.	DENND2C isoform 3.	0.718
CHM	DENND2C	ENSPPYP00000022968	ENSPPYP00000001167	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	DENND2C isoform 3.	0.449
CHM	IFT27	ENSPPYP00000022968	ENSPPYP00000013140	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Intraflagellar transport 27.	0.527
CHM	RAB35	ENSPPYP00000022968	ENSPPYP00000005723	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	RAB35, member RAS oncogene family.	0.859
CHM	RAB9B	ENSPPYP00000022968	ENSPPYP00000023047	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network.	0.885
CR201_G0031594	DENND2C	ENSPPYP00000003436	ENSPPYP00000001167	TPCN2 isoform 7.	DENND2C isoform 3.	0.409
DENND2C	AVL9	ENSPPYP00000001167	ENSPPYP00000019795	DENND2C isoform 3.	Late secretory pathway protein AVL9 homolog; Functions in cell migration; Belongs to the AVL9 family.	0.514
DENND2C	C3orf67	ENSPPYP00000001167	ENSPPYP00000015387	DENND2C isoform 3.	C3orf67 isoform 1.	0.718
DENND2C	CHM	ENSPPYP00000001167	ENSPPYP00000022968	DENND2C isoform 3.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.449
DENND2C	CR201_G0031594	ENSPPYP00000001167	ENSPPYP00000003436	DENND2C isoform 3.	TPCN2 isoform 7.	0.409
DENND2C	IFT27	ENSPPYP00000001167	ENSPPYP00000013140	DENND2C isoform 3.	Intraflagellar transport 27.	0.528
DENND2C	NRROS	ENSPPYP00000001167	ENSPPYP00000016153	DENND2C isoform 3.	NRROS isoform 1.	0.485
DENND2C	RAB35	ENSPPYP00000001167	ENSPPYP00000005723	DENND2C isoform 3.	RAB35, member RAS oncogene family.	0.528
DENND2C	RAB9B	ENSPPYP00000001167	ENSPPYP00000023047	DENND2C isoform 3.	Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network.	0.765
DENND2C	RHOBTB3	ENSPPYP00000001167	ENSPPYP00000017489	DENND2C isoform 3.	RHOBTB3 isoform 7.	0.629
DENND2C	SYTL1	ENSPPYP00000001167	ENSPPYP00000001924	DENND2C isoform 3.	Synaptotagmin like 1.	0.486
IFT27	CHM	ENSPPYP00000013140	ENSPPYP00000022968	Intraflagellar transport 27.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.527
IFT27	DENND2C	ENSPPYP00000013140	ENSPPYP00000001167	Intraflagellar transport 27.	DENND2C isoform 3.	0.528