PTPN22 protein (Pongo abelii) - STRING interaction network

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Score

PTPN22

Protein tyrosine phosphatase non-receptor type 22. (807 aa)

Predicted Functional Partners:

CSK

0.929

EGFR

0.913

SHC1

0.887

PSTPIP1

0.867

LCK

0.834

PSTPIP2

0.768

SHC3

0.757

MATK

0.756

ZAP70

0.731

CTLA4

0.693

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSK	EGFR	ENSPPYP00000007539	ENSPPYP00000019671	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.955
CSK	LCK	ENSPPYP00000007539	ENSPPYP00000001840	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.739
CSK	MATK	ENSPPYP00000007539	ENSPPYP00000010529	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.516
CSK	PTPN22	ENSPPYP00000007539	ENSPPYP00000001176	Tyrosine-protein kinase.	Protein tyrosine phosphatase non-receptor type 22.	0.929
CSK	SHC1	ENSPPYP00000007539	ENSPPYP00000000893	Tyrosine-protein kinase.	SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity).	0.888
CSK	SHC3	ENSPPYP00000007539	ENSPPYP00000021691	Tyrosine-protein kinase.	SHC3 isoform 1.	0.685
CSK	ZAP70	ENSPPYP00000007539	ENSPPYP00000013469	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.503
CTLA4	EGFR	ENSPPYP00000014639	ENSPPYP00000019671	Cytotoxic T-lymphocyte associated protein 4.	Receptor protein-tyrosine kinase.	0.482
CTLA4	LCK	ENSPPYP00000014639	ENSPPYP00000001840	Cytotoxic T-lymphocyte associated protein 4.	Tyrosine-protein kinase.	0.721
CTLA4	PTPN22	ENSPPYP00000014639	ENSPPYP00000001176	Cytotoxic T-lymphocyte associated protein 4.	Protein tyrosine phosphatase non-receptor type 22.	0.693
CTLA4	ZAP70	ENSPPYP00000014639	ENSPPYP00000013469	Cytotoxic T-lymphocyte associated protein 4.	Tyrosine-protein kinase.	0.540
EGFR	CSK	ENSPPYP00000019671	ENSPPYP00000007539	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.955
EGFR	CTLA4	ENSPPYP00000019671	ENSPPYP00000014639	Receptor protein-tyrosine kinase.	Cytotoxic T-lymphocyte associated protein 4.	0.482
EGFR	LCK	ENSPPYP00000019671	ENSPPYP00000001840	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.755
EGFR	MATK	ENSPPYP00000019671	ENSPPYP00000010529	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.828
EGFR	PTPN22	ENSPPYP00000019671	ENSPPYP00000001176	Receptor protein-tyrosine kinase.	Protein tyrosine phosphatase non-receptor type 22.	0.913
EGFR	SHC1	ENSPPYP00000019671	ENSPPYP00000000893	Receptor protein-tyrosine kinase.	SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity).	0.996
EGFR	SHC3	ENSPPYP00000019671	ENSPPYP00000021691	Receptor protein-tyrosine kinase.	SHC3 isoform 1.	0.991
EGFR	ZAP70	ENSPPYP00000019671	ENSPPYP00000013469	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase.	0.812
LCK	CSK	ENSPPYP00000001840	ENSPPYP00000007539	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.739