Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHTF1Putative homeodomain transcription factor 1. (762 aa)    
Predicted Functional Partners:
PHTF2
PHTF2 isoform 2.
    
   0.709
RSBN1
Round spermatid basic protein 1.
 
    
 0.675
MSL3
Male-specific lethal 3 homolog; May be involved in chromatin remodeling and transcriptional regulation. May have a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex (By similarity).
    
 0.654
MSL2
MSL2 isoform 4.
    
 0.649
SWT1
SWT1 RNA endoribonuclease homolog.
    
 
 0.624
GPR156
GPR156 isoform 1.
    
   0.554
NAGK
N-acetylglucosamine kinase.
   
  
 0.551
BCL2L15
BCL2L15 isoform 1.
   
  
 0.540
CR201_G0000883
HNF1A isoform 7.
    
 0.518
MAGI3
MAGI3 isoform 2.
    
 0.507
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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