LRIF1 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LRIF1

LRIF1 isoform 1. (742 aa)

Predicted Functional Partners:

SMCHD1

0.756

CBX5

0.503

ENSPPYP00000017070

0.457

CBX3

0.417

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBX3	CBX5	ENSPPYP00000019856	ENSPPYP00000005247	Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the [...]	CBX5 isoform 2.	0.714
CBX3	LRIF1	ENSPPYP00000019856	ENSPPYP00000001211	Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the [...]	LRIF1 isoform 1.	0.417
CBX5	CBX3	ENSPPYP00000005247	ENSPPYP00000019856	CBX5 isoform 2.	Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the [...]	0.714
CBX5	LRIF1	ENSPPYP00000005247	ENSPPYP00000001211	CBX5 isoform 2.	LRIF1 isoform 1.	0.503
ENSPPYP00000017070	LRIF1	ENSPPYP00000017070	ENSPPYP00000001211	annotation not available	LRIF1 isoform 1.	0.457
ENSPPYP00000017070	SMCHD1	ENSPPYP00000017070	ENSPPYP00000010141	annotation not available	SMCHD1 isoform 1.	0.744
LRIF1	CBX3	ENSPPYP00000001211	ENSPPYP00000019856	LRIF1 isoform 1.	Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the [...]	0.417
LRIF1	CBX5	ENSPPYP00000001211	ENSPPYP00000005247	LRIF1 isoform 1.	CBX5 isoform 2.	0.503
LRIF1	ENSPPYP00000017070	ENSPPYP00000001211	ENSPPYP00000017070	LRIF1 isoform 1.	annotation not available	0.457
LRIF1	SMCHD1	ENSPPYP00000001211	ENSPPYP00000010141	LRIF1 isoform 1.	SMCHD1 isoform 1.	0.756
SMCHD1	ENSPPYP00000017070	ENSPPYP00000010141	ENSPPYP00000017070	SMCHD1 isoform 1.	annotation not available	0.744
SMCHD1	LRIF1	ENSPPYP00000010141	ENSPPYP00000001211	SMCHD1 isoform 1.	LRIF1 isoform 1.	0.756