Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PROK1PROK1 isoform 1. (105 aa)    
Predicted Functional Partners:
PROKR2
Prokineticin receptor 2.
    
 0.671
PROKR1
APLF isoform 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.671
IGFBP1
IGFBP1 isoform 1.
      
 0.570
IL11
IL11 isoform 1.
      
 0.509
SGK1
Non-specific serine/threonine protein kinase.
      
 0.501
WT1
WT1 isoform 2.
      
 0.500
PRLHR
Prolactin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.483
MCHR2
Melanin concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.479
MEIS1
MEIS1 isoform 1.
      
 0.477
MAP6
MAP6 isoform 1.
     
 0.419
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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