Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RBM15RNA binding motif protein 15. (969 aa)    
Predicted Functional Partners:
WTAP
WT1 associated protein.
    
 0.894
ZC3H13
ZC3H13 isoform 2.
   
 0.861
METTL3
Methyltransferase like 3; Belongs to the MT-A70-like family.
    
 0.855
VIRMA
VIRMA isoform 1.
   
 0.846
METTL14
N6-adenosine-methyltransferase non-catalytic subunit; The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing (By simila [...]
    
 0.777
ALYREF
Aly/REF export factor.
    
 
 0.776
YTHDC1
YTHDC1 isoform 1.
   
  
 0.558
MRTFA
MKL1 isoform 5.
   
  
 0.539
CBLL1
CBLL1 isoform 1.
     
 0.536
CBLL2
Cbl proto-oncogene like 2.
     
 0.536
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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