Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPS8L3EPS8L3 isoform 5. (593 aa)    
Predicted Functional Partners:
CASK
CASK isoform 2; Belongs to the MAGUK family.
   
 0.675
LPAR6
Lysophosphatidic acid receptor 6.
   
  
 0.652
DSG4
DSG4 isoform 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
      
 0.625
APCDD1
APCDD1 isoform 1.
      
 0.584
FCSK
FUK isoform 2.
      
 0.568
USH1C
USH1C isoform 9.
   
 
 0.563
VAC14
VAC14 component of PIKFYVE complex.
      
 0.532
MTSS1L
MTSS1L isoform 1.
      
 0.531
CDSN
CDSN isoform 1.
   
  
 0.527
COG4
Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1.
      
 0.526
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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