STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSTM5GSTM1 isoform 5; Belongs to the GST superfamily. (218 aa)    
Predicted Functional Partners:
GSTM3
Glutathione S-transferase.
  
0.965
GSTM1
Glutathione S-transferase Mu 2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family.
  
 
 
0.924
CYP2E1
CYP2E1 isoform 1; Belongs to the cytochrome P450 family.
   
 
 0.913
LOC100461022
GSTT2B isoform 1; Belongs to the GST superfamily.
    
 0.844
GSTO1
Glutathione S-transferase omega 1.
   
 0.836
GSTO2
Glutathione S-transferase omega 2; Belongs to the GST superfamily.
   
 0.817
GSTA5
LOW QUALITY PROTEIN: glutathione S-transferase A5.
   
 
0.811
PRDX6
Peroxiredoxin 6.
   
 0.807
LOC100447051
Peroxiredoxin-6; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, and can therefore either reduce the oxidized sn-2 fatty acyl grup of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role [...]
   
 0.807
GSTA4
Glutathione S-transferase alpha 4; Belongs to the GST superfamily.
   
 
 0.804
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.