GNAI3 protein (Pongo abelii) - STRING interaction network

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GNAI3

Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...] (354 aa)

Predicted Functional Partners:

GNAI2

0.997

GNAI1

0.995

GNB1

0.991

GPSM1

0.988

GNB2

0.987

ENSPPYP00000007387

0.982

GNAO1

0.980

CASR

0.979

SSTR2

0.977

ENSPPYP00000002678

0.975

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASR	ENSPPYP00000002678	ENSPPYP00000015087	ENSPPYP00000002678	Calcium sensing receptor.	annotation not available	0.603
CASR	GNAI1	ENSPPYP00000015087	ENSPPYP00000020020	Calcium sensing receptor.	Guanine nucleotide-binding protein G(i) subunit alpha-1.	0.735
CASR	GNAI2	ENSPPYP00000015087	ENSPPYP00000015499	Calcium sensing receptor.	GNAI2 isoform 1.	0.958
CASR	GNAI3	ENSPPYP00000015087	ENSPPYP00000001241	Calcium sensing receptor.	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	0.979
CASR	GNAO1	ENSPPYP00000015087	ENSPPYP00000008317	Calcium sensing receptor.	GNAO1 isoform 1.	0.573
CASR	GNB1	ENSPPYP00000015087	ENSPPYP00000002307	Calcium sensing receptor.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.663
CASR	GNB2	ENSPPYP00000015087	ENSPPYP00000019528	Calcium sensing receptor.	GNB2 isoform 1.	0.663
ENSPPYP00000002678	CASR	ENSPPYP00000002678	ENSPPYP00000015087	annotation not available	Calcium sensing receptor.	0.603
ENSPPYP00000002678	ENSPPYP00000007387	ENSPPYP00000002678	ENSPPYP00000007387	annotation not available	annotation not available	0.862
ENSPPYP00000002678	GNAI1	ENSPPYP00000002678	ENSPPYP00000020020	annotation not available	Guanine nucleotide-binding protein G(i) subunit alpha-1.	0.975
ENSPPYP00000002678	GNAI3	ENSPPYP00000002678	ENSPPYP00000001241	annotation not available	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	0.975
ENSPPYP00000002678	GNAO1	ENSPPYP00000002678	ENSPPYP00000008317	annotation not available	GNAO1 isoform 1.	0.666
ENSPPYP00000002678	GNB1	ENSPPYP00000002678	ENSPPYP00000002307	annotation not available	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.919
ENSPPYP00000002678	GNB2	ENSPPYP00000002678	ENSPPYP00000019528	annotation not available	GNB2 isoform 1.	0.869
ENSPPYP00000002678	GPSM1	ENSPPYP00000002678	ENSPPYP00000022167	annotation not available	GPSM1 isoform 3.	0.679
ENSPPYP00000002678	SSTR2	ENSPPYP00000002678	ENSPPYP00000009640	annotation not available	Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.405
ENSPPYP00000007387	ENSPPYP00000002678	ENSPPYP00000007387	ENSPPYP00000002678	annotation not available	annotation not available	0.862
ENSPPYP00000007387	GNAI1	ENSPPYP00000007387	ENSPPYP00000020020	annotation not available	Guanine nucleotide-binding protein G(i) subunit alpha-1.	0.950
ENSPPYP00000007387	GNAI2	ENSPPYP00000007387	ENSPPYP00000015499	annotation not available	GNAI2 isoform 1.	0.949
ENSPPYP00000007387	GNAI3	ENSPPYP00000007387	ENSPPYP00000001241	annotation not available	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	0.982

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