GPR61 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRA2	ADGRG3	ENSPPYP00000020751	ENSPPYP00000008357	ADGRA2 isoform 2; Belongs to the G-protein coupled receptor 2 family.	ADGRG3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.597
ADGRA2	GPR61	ENSPPYP00000020751	ENSPPYP00000001242	ADGRA2 isoform 2; Belongs to the G-protein coupled receptor 2 family.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.715
ADGRA2	GPRC5C	ENSPPYP00000020751	ENSPPYP00000009654	ADGRA2 isoform 2; Belongs to the G-protein coupled receptor 2 family.	GPRC5C isoform 2.	0.576
ADGRG3	ADGRA2	ENSPPYP00000008357	ENSPPYP00000020751	ADGRG3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	ADGRA2 isoform 2; Belongs to the G-protein coupled receptor 2 family.	0.597
ADGRG3	ADGRG5	ENSPPYP00000008357	ENSPPYP00000008353	ADGRG3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	ADGRG5 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.482
ADGRG3	GNB1	ENSPPYP00000008357	ENSPPYP00000002307	ADGRG3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.740
ADGRG3	GPR61	ENSPPYP00000008357	ENSPPYP00000001242	ADGRG3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.722
ADGRG3	GPRC5C	ENSPPYP00000008357	ENSPPYP00000009654	ADGRG3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	GPRC5C isoform 2.	0.526
ADGRG5	ADGRG3	ENSPPYP00000008353	ENSPPYP00000008357	ADGRG5 isoform 1; Belongs to the G-protein coupled receptor 2 family.	ADGRG3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.482
ADGRG5	GNB1	ENSPPYP00000008353	ENSPPYP00000002307	ADGRG5 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.452
ADGRG5	GPR61	ENSPPYP00000008353	ENSPPYP00000001242	ADGRG5 isoform 1; Belongs to the G-protein coupled receptor 2 family.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.519
ADGRG5	GPRC5C	ENSPPYP00000008353	ENSPPYP00000009654	ADGRG5 isoform 1; Belongs to the G-protein coupled receptor 2 family.	GPRC5C isoform 2.	0.486
AMHR2	GPR61	ENSPPYP00000005223	ENSPPYP00000001242	Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.622
FST	GPR61	ENSPPYP00000017271	ENSPPYP00000001242	FST isoform 1.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.522
GJB6	GPR61	ENSPPYP00000005914	ENSPPYP00000001242	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.523
GNB1	ADGRG3	ENSPPYP00000002307	ENSPPYP00000008357	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	ADGRG3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.740
GNB1	ADGRG5	ENSPPYP00000002307	ENSPPYP00000008353	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	ADGRG5 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.452
GNB1	GPR61	ENSPPYP00000002307	ENSPPYP00000001242	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	0.560
GPR61	ADGRA2	ENSPPYP00000001242	ENSPPYP00000020751	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	ADGRA2 isoform 2; Belongs to the G-protein coupled receptor 2 family.	0.715
GPR61	ADGRG3	ENSPPYP00000001242	ENSPPYP00000008357	G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.	ADGRG3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.722