SYPL2 protein (Pongo abelii) - STRING interaction network

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Score

SYPL2

Synaptophysin like 2. (272 aa)

Predicted Functional Partners:

GRID1

0.730

CAMK2A

0.725

GRID2

0.691

CBLN4

0.628

VAMP1

0.619

VAMP2

0.619

NRXN2

0.579

SNAP25

0.557

CBLN1

0.551

RXRG

0.540

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAMK2A	GRID1	ENSPPYP00000017843	ENSPPYP00000002649	Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcriptio [...]	GRID1 isoform 1.	0.538
CAMK2A	GRID2	ENSPPYP00000017843	ENSPPYP00000016675	Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcriptio [...]	GRID2 isoform 1.	0.530
CAMK2A	NRXN2	ENSPPYP00000017843	ENSPPYP00000003585	Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcriptio [...]	NRXN2 isoform 3.	0.614
CAMK2A	SNAP25	ENSPPYP00000017843	ENSPPYP00000011970	Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcriptio [...]	Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.	0.403
CAMK2A	SYPL2	ENSPPYP00000017843	ENSPPYP00000001246	Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcriptio [...]	Synaptophysin like 2.	0.725
CBLN1	GRID1	ENSPPYP00000008280	ENSPPYP00000002649	Cerebellin 1 precursor.	GRID1 isoform 1.	0.720
CBLN1	GRID2	ENSPPYP00000008280	ENSPPYP00000016675	Cerebellin 1 precursor.	GRID2 isoform 1.	0.806
CBLN1	NRXN2	ENSPPYP00000008280	ENSPPYP00000003585	Cerebellin 1 precursor.	NRXN2 isoform 3.	0.573
CBLN1	RXRG	ENSPPYP00000008280	ENSPPYP00000000669	Cerebellin 1 precursor.	Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).	0.468
CBLN1	SYPL2	ENSPPYP00000008280	ENSPPYP00000001246	Cerebellin 1 precursor.	Synaptophysin like 2.	0.551
CBLN4	GRID1	ENSPPYP00000012453	ENSPPYP00000002649	Cerebellin 4 precursor.	GRID1 isoform 1.	0.699
CBLN4	RXRG	ENSPPYP00000012453	ENSPPYP00000000669	Cerebellin 4 precursor.	Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).	0.525
CBLN4	SYPL2	ENSPPYP00000012453	ENSPPYP00000001246	Cerebellin 4 precursor.	Synaptophysin like 2.	0.628
GRID1	CAMK2A	ENSPPYP00000002649	ENSPPYP00000017843	GRID1 isoform 1.	Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcriptio [...]	0.538
GRID1	CBLN1	ENSPPYP00000002649	ENSPPYP00000008280	GRID1 isoform 1.	Cerebellin 1 precursor.	0.720
GRID1	CBLN4	ENSPPYP00000002649	ENSPPYP00000012453	GRID1 isoform 1.	Cerebellin 4 precursor.	0.699
GRID1	GRID2	ENSPPYP00000002649	ENSPPYP00000016675	GRID1 isoform 1.	GRID2 isoform 1.	0.748
GRID1	SYPL2	ENSPPYP00000002649	ENSPPYP00000001246	GRID1 isoform 1.	Synaptophysin like 2.	0.730
GRID2	CAMK2A	ENSPPYP00000016675	ENSPPYP00000017843	GRID2 isoform 1.	Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcriptio [...]	0.530
GRID2	CBLN1	ENSPPYP00000016675	ENSPPYP00000008280	GRID2 isoform 1.	Cerebellin 1 precursor.	0.806