Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MYBPHLMYBPHL isoform 1. (352 aa)    
Predicted Functional Partners:
MYBPH
Myosin binding protein H.
  
  
 
0.901
CR201_G0012702
TACC2 isoform 1.
      
 0.636
AMHR2
Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
      
 0.633
PSMB4
Proteasome subunit beta; Belongs to the peptidase T1B family.
      
 0.525
CCS
Copper chaperone for superoxide dismutase.
      
 0.525
PRPF19
PRPF19 isoform 1.
      
 0.525
RHEB
RHEB isoform 1.
      
 0.521
CR201_G0012702-2
TACC2 isoform 5.
      
 0.509
RHEBL1
RHEBL1 isoform 2.
      
 0.491
PSMG1
Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
      
 0.491
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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