Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSRC1Proline and serine rich coiled-coil 1. (333 aa)    
Predicted Functional Partners:
CELSR2
CELSR2 isoform 1; Belongs to the G-protein coupled receptor 2 family.
      
 0.762
SORT1
Sortilin.
      
 0.718
MAPRE1
Microtubule-associated protein RP/EB family member 1; Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, a [...]
    
 
 0.670
AURKA
AURKA isoform 10; Belongs to the protein kinase superfamily.
   
 
 0.601
DLGAP5
DLGAP5 isoform 1.
   
  
 0.600
CDCA3
CDCA3 isoform 4.
   
  
 0.590
GAS2L3
GAS2L3 isoform 2.
      
 0.579
DDIAS
DNA damage induced apoptosis suppressor.
   
  
 0.530
SYPL2
Synaptophysin like 2.
      
 0.523
SNAP47
SNAP47 isoform 1.
      
 0.513
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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