Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CELSR2CELSR2 isoform 1; Belongs to the G-protein coupled receptor 2 family. (2910 aa)    
Predicted Functional Partners:
VANGL1
Vang-like protein.
    
 0.780
PSRC1
Proline and serine rich coiled-coil 1.
      
 0.762
SORT1
Sortilin.
      
 0.701
VANGL2
Vang-like protein.
    
 0.699
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
 0.554
MROH2B
MROH2B isoform 5.
      
 0.515
ANKRD6
Ankyrin repeat domain 6.
    
 0.503
MAST4
MAST4 isoform 5.
   
  
 0.495
RYK
RYK isoform 3.
   
  
 0.493
FZD3
Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.489
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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