Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RNPC3RNA-binding region-containing protein 3; Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'- stem-loop of m(7)G-capped U12 snRNA (By similarity). (438 aa)    
Predicted Functional Partners:
ZMAT5
Zinc finger matrin-type 5.
   
 0.996
ZCRB1
Zinc finger CCHC-type and RNA binding motif containing 1.
   
 0.992
SNRNP35
Small nuclear ribonucleoprotein U11/U12 subunit 35.
   
 0.981
ZRSR2
Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2.
   
 0.970
SNRPF
Small nuclear ribonucleoprotein polypeptide F.
   
 0.966
SF3B1
SF3B1 isoform 1.
   
 0.959
ENSPPYP00000001065
annotation not available
   
 0.941
SF3B5
Splicing factor 3B subunit 5; Belongs to the SF3B5 family.
   
 0.935
SNRPD1
Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
   
 0.928
SF3B2
SF3B2 isoform 4.
   
 0.921
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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