S1PR1 protein (Pongo abelii) - STRING interaction network

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Score

S1PR1

S1PR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)

Predicted Functional Partners:

GNAI3

0.955

GNAI2

0.940

NFATC1

0.908

NFATC4

0.900

NFATC3

0.900

S1PR4

0.900

NFATC2

0.900

CD69

0.872

GNAI1

0.780

GNB1

0.773

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD69	GNAI1	ENSPPYP00000004856	ENSPPYP00000020020	CD69 isoform 3.	Guanine nucleotide-binding protein G(i) subunit alpha-1.	0.532
CD69	GNB1	ENSPPYP00000004856	ENSPPYP00000002307	CD69 isoform 3.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.532
CD69	S1PR1	ENSPPYP00000004856	ENSPPYP00000001284	CD69 isoform 3.	S1PR1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.872
CD69	S1PR4	ENSPPYP00000004856	ENSPPYP00000010509	CD69 isoform 3.	Sphingosine-1-phosphate receptor 4.	0.480
GNAI1	CD69	ENSPPYP00000020020	ENSPPYP00000004856	Guanine nucleotide-binding protein G(i) subunit alpha-1.	CD69 isoform 3.	0.532
GNAI1	GNAI2	ENSPPYP00000020020	ENSPPYP00000015499	Guanine nucleotide-binding protein G(i) subunit alpha-1.	GNAI2 isoform 1.	0.975
GNAI1	GNAI3	ENSPPYP00000020020	ENSPPYP00000001241	Guanine nucleotide-binding protein G(i) subunit alpha-1.	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	0.995
GNAI1	GNB1	ENSPPYP00000020020	ENSPPYP00000002307	Guanine nucleotide-binding protein G(i) subunit alpha-1.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.973
GNAI1	S1PR1	ENSPPYP00000020020	ENSPPYP00000001284	Guanine nucleotide-binding protein G(i) subunit alpha-1.	S1PR1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.780
GNAI1	S1PR4	ENSPPYP00000020020	ENSPPYP00000010509	Guanine nucleotide-binding protein G(i) subunit alpha-1.	Sphingosine-1-phosphate receptor 4.	0.424
GNAI2	GNAI1	ENSPPYP00000015499	ENSPPYP00000020020	GNAI2 isoform 1.	Guanine nucleotide-binding protein G(i) subunit alpha-1.	0.975
GNAI2	GNAI3	ENSPPYP00000015499	ENSPPYP00000001241	GNAI2 isoform 1.	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	0.997
GNAI2	GNB1	ENSPPYP00000015499	ENSPPYP00000002307	GNAI2 isoform 1.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.970
GNAI2	S1PR1	ENSPPYP00000015499	ENSPPYP00000001284	GNAI2 isoform 1.	S1PR1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.940
GNAI2	S1PR4	ENSPPYP00000015499	ENSPPYP00000010509	GNAI2 isoform 1.	Sphingosine-1-phosphate receptor 4.	0.939
GNAI3	GNAI1	ENSPPYP00000001241	ENSPPYP00000020020	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	Guanine nucleotide-binding protein G(i) subunit alpha-1.	0.995
GNAI3	GNAI2	ENSPPYP00000001241	ENSPPYP00000015499	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	GNAI2 isoform 1.	0.997
GNAI3	GNB1	ENSPPYP00000001241	ENSPPYP00000002307	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.991
GNAI3	S1PR1	ENSPPYP00000001241	ENSPPYP00000001284	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	S1PR1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.955
GNAI3	S1PR4	ENSPPYP00000001241	ENSPPYP00000010509	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	Sphingosine-1-phosphate receptor 4.	0.939