Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EXTL2Exostosin like glycosyltransferase 2. (330 aa)    
Predicted Functional Partners:
EXTL3
Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.
    
0.973
EXT1
Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).
    
0.965
B3GAT3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.
     
 0.937
EXT2
Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.
     
0.912
CSGALNACT2
Hexosyltransferase.
    
 
 0.724
EXTL1
Exostosin like glycosyltransferase 1; Belongs to the glycosyltransferase 47 family.
    
 0.671
GJC2
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
   0.667
NDST2
T0105225 isoform 1.
    
 
 0.639
CSGALNACT1
Hexosyltransferase.
    
 
 0.617
CHST11
Carbohydrate sulfotransferase.
      
 0.570
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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