Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC14ACell division cycle 14A. (594 aa)    
Predicted Functional Partners:
CDC14B
Cell division cycle 14B.
  
  
 
0.921
ENSPPYP00000019690
LOW QUALITY PROTEIN: dual specificity protein phosphatase CDC14C.
  
  
 
0.920
FZR1
FZR1 isoform 4.
   
 0.918
AHSP
Alpha hemoglobin stabilizing protein.
      
 0.854
ESPL1
ESPL1 isoform 1.
   
 
 0.779
MAPK6
Mitogen-activated protein kinase 6; Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase s [...]
    
 0.777
CDC20
Cell division cycle 20.
   
 0.735
CDC23
Cell division cycle 23.
     
 0.729
CDC27
CDC27 isoform 1.
   
 0.726
CDC16
CDC16 isoform 4.
     
 0.715
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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