SASS6 protein (Pongo abelii) - STRING interaction network

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Score

SASS6

SAS-6 centriolar assembly protein. (657 aa)

Predicted Functional Partners:

STIL

0.962

CENPJ

0.956

PLK4

0.921

WRN

0.855

FANCM

0.838

FYCO1

0.830

CEP135

0.827

CEP192

0.810

MEIOB

0.807

CEP152

0.797

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CENPJ	CEP135	ENSPPYP00000005941	ENSPPYP00000016481	CENPJ isoform 2.	CEP135 isoform 2.	0.953
CENPJ	CEP152	ENSPPYP00000005941	ENSPPYP00000007316	CENPJ isoform 2.	CEP152 isoform 2.	0.967
CENPJ	CEP192	ENSPPYP00000005941	ENSPPYP00000024129	CENPJ isoform 2.	CEP192 isoform 7.	0.741
CENPJ	PLK4	ENSPPYP00000005941	ENSPPYP00000016820	CENPJ isoform 2.	Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Phosphorylates 'Ser-151' of FBXW5 during the G1/S transition, leading to inhibit [...]	0.945
CENPJ	SASS6	ENSPPYP00000005941	ENSPPYP00000001299	CENPJ isoform 2.	SAS-6 centriolar assembly protein.	0.956
CENPJ	STIL	ENSPPYP00000005941	ENSPPYP00000001600	CENPJ isoform 2.	STIL isoform 3.	0.966
CEP135	CENPJ	ENSPPYP00000016481	ENSPPYP00000005941	CEP135 isoform 2.	CENPJ isoform 2.	0.953
CEP135	CEP152	ENSPPYP00000016481	ENSPPYP00000007316	CEP135 isoform 2.	CEP152 isoform 2.	0.840
CEP135	CEP192	ENSPPYP00000016481	ENSPPYP00000024129	CEP135 isoform 2.	CEP192 isoform 7.	0.708
CEP135	PLK4	ENSPPYP00000016481	ENSPPYP00000016820	CEP135 isoform 2.	Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Phosphorylates 'Ser-151' of FBXW5 during the G1/S transition, leading to inhibit [...]	0.867
CEP135	SASS6	ENSPPYP00000016481	ENSPPYP00000001299	CEP135 isoform 2.	SAS-6 centriolar assembly protein.	0.827
CEP135	STIL	ENSPPYP00000016481	ENSPPYP00000001600	CEP135 isoform 2.	STIL isoform 3.	0.626
CEP152	CENPJ	ENSPPYP00000007316	ENSPPYP00000005941	CEP152 isoform 2.	CENPJ isoform 2.	0.967
CEP152	CEP135	ENSPPYP00000007316	ENSPPYP00000016481	CEP152 isoform 2.	CEP135 isoform 2.	0.840
CEP152	CEP192	ENSPPYP00000007316	ENSPPYP00000024129	CEP152 isoform 2.	CEP192 isoform 7.	0.856
CEP152	PLK4	ENSPPYP00000007316	ENSPPYP00000016820	CEP152 isoform 2.	Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Phosphorylates 'Ser-151' of FBXW5 during the G1/S transition, leading to inhibit [...]	0.991
CEP152	SASS6	ENSPPYP00000007316	ENSPPYP00000001299	CEP152 isoform 2.	SAS-6 centriolar assembly protein.	0.797
CEP152	STIL	ENSPPYP00000007316	ENSPPYP00000001600	CEP152 isoform 2.	STIL isoform 3.	0.826
CEP192	CENPJ	ENSPPYP00000024129	ENSPPYP00000005941	CEP192 isoform 7.	CENPJ isoform 2.	0.741
CEP192	CEP135	ENSPPYP00000024129	ENSPPYP00000016481	CEP192 isoform 7.	CEP135 isoform 2.	0.708