Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PALMDPALMD isoform 2. (551 aa)    
Predicted Functional Partners:
LRMDA
Leucine rich melanocyte differentiation associated.
      
 0.721
CLVS1
Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).
      
 0.719
IGSF21
IGSF21 isoform 1.
    
 
 0.686
ADGRL2
ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.
   
 
 0.685
VPS13C
VPS13C isoform 1.
      
 0.667
KCNH7
KCNH7 isoform 2.
      
 0.648
C12orf45
Chromosome 12 open reading frame 45.
    
 
 0.623
TBX15
T-box transcription factor 15.
      
 0.606
RNF145
RNF145 isoform 7.
      
 0.602
ASTN2
ASTN2 isoform 3.
    
 
 0.599
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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