Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TLCD4TLC domain containing 4. (263 aa)    
Predicted Functional Partners:
RASSF3
RASSF3 isoform 4.
      
 0.586
METTL8
Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family.
      
 0.579
LRGUK
LRGUK isoform 1.
    
 
 0.552
NOCT
NOCT isoform 2.
    
 
 0.531
SBK1
Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
  
 0.527
KDELR3
ER lumen protein-retaining receptor.
    
   0.502
RGS7BP
Regulator of G protein signaling 7 binding protein.
      
 0.501
IPCEF1
IPCEF1 isoform 2.
      
 0.496
NRIP2
Nuclear receptor interacting protein 2.
      
 0.486
SBF2
SET binding factor 2.
      
 0.485
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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