Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)    
Predicted Functional Partners:
GCLC
Glutamate-cysteine ligase catalytic subunit.
   
 0.999
GSS
Glutathione synthetase.
   
 0.983
OPLAH
OPLAH isoform 1.
   
 
 0.937
ANPEP
Aminopeptidase.
   
 
  0.921
GGT7
GGT7 isoform 2.
   
 
 0.916
GGT6
Gamma-glutamyltransferase 6.
   
 
 0.911
BCAT1
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 0.910
BCAT2
Branched-chain-amino-acid aminotransferase, mitochondrial; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids (By similarity).
   
 0.910
GGT1
GGT2 isoform 2.
   
 
 0.910
GGT5
GGT5 isoform 2.
   
 
 0.909
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (32%) [HD]