Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIPK1ADivergent protein kinase domain 1A; Belongs to the DIPK family. (428 aa)    
Predicted Functional Partners:
CR201_G0003096
FAM136A isoform 1.
      
 0.632
CCDC126
Coiled-coil domain containing 126.
      
 0.625
ABHD13
Abhydrolase domain containing 13.
      
 0.624
TMEM219
Transmembrane protein 219.
    
 
 0.593
CCDC159
CCDC159 isoform 1.
      
 0.533
CR201_G0027646
RALGPS1 isoform 3.
      
 0.529
SLC43A1
SLC43A1 isoform 1.
    
 
 0.516
C5H5orf22
UPF0489 protein C5orf22 homolog; Belongs to the UPF0489 family.
      
 0.485
TSKU
Tsukushi, small leucine rich proteoglycan.
    
 
 0.474
ACSS3
Acyl-CoA synthetase short-chain family member 3, mitochondrial; Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids (By similarity). Propionate is the preferred substrate but can also utilize acetate and butyrate with a much lower affinity.
      
 0.437
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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