Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BRDTBRDT isoform 3. (939 aa)    
Predicted Functional Partners:
BRD4
Bromodomain containing 4.
    
 
 0.919
FUBP1
FUBP1 isoform 8.
   
 
 0.848
CR201_G0027625
CDK9 isoform 1; Belongs to the protein kinase superfamily.
   
 
 0.772
ASF1B
ASF1B isoform 4.
    
 
 0.762
BRD2
BRD2 isoform 1.
    
 
 0.746
TK1
Thymidine kinase.
      
 0.718
TOP2A
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
 
 0.706
HNRNPDL
Heterogeneous nuclear ribonucleoprotein D like.
   
 
 0.705
PBK
PDZ binding kinase.
    
 
 0.700
CCNT1
CCNT1 isoform 2; Belongs to the cyclin family.
   
 
 0.692
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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