Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNF644ZNF644 isoform 2. (1327 aa)    
Predicted Functional Partners:
EHMT2
EHMT2 isoform 5.
   
 0.820
CR201_G0037536
WIZ isoform 3.
   
 
 0.790
KCTD11
Potassium channel tetramerization domain containing 11.
     
 0.778
SLC12A6
SLC12A6 isoform 1.
    
 
 0.745
EPS8
Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...]
    
 
 0.731
ARGLU1
ARGLU1 isoform 3.
   
  0.716
CDYL
Chromodomain Y like.
    
 0.715
EHMT1
EHMT1 isoform 1.
   
 0.681
ZNF292
ZNF292 isoform 2.
  
 
 0.659
CCDC24
CCDC24 isoform 2.
      
 0.627
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (24%) [HD]