Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRC8DLeucine rich repeat containing 8 VRAC subunit D. (858 aa)    
Predicted Functional Partners:
LRRC8A
Leucine rich repeat containing 8 VRAC subunit A.
   
  0.964
LRRC8B
LRRC8B isoform 1.
    
  0.899
LRRIQ4
LRRIQ4 isoform 1.
  
 
0.568
LRRC8C
Leucine rich repeat containing 8 VRAC subunit C.
   
  0.529
LRRC8E
Leucine rich repeat containing 8 VRAC subunit E.
   
  0.529
KERA
KERA isoform 1.
  
     0.424
CHST7
Sulfotransferase; Belongs to the sulfotransferase 1 family.
     
 0.418
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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