Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GBP6Guanylate-binding protein 6; Binds GTP, GDP and GMP. (634 aa)    
Predicted Functional Partners:
LGALS8
Galectin.
   
 
 0.525
PYHIN1
PYHIN1 isoform 4.
   
  
 0.516
HERC6
HERC6 isoform 3.
   
  
 0.514
CASP4
CASP4 isoform 2; Belongs to the peptidase C14A family.
   
 0.479
SFN
SFN isoform 1; Belongs to the 14-3-3 family.
    
  0.451
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
   
 
 0.438
CR201_G0052494
PCSK4 isoform 7.
   
 
 0.438
PIM2
Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
    
  0.414
GBP5
GBP5 isoform 2.
   
  0.411
PGGT1B
PGGT1B isoform 1.
     
  0.403
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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