GBP2 protein (Pongo abelii) - STRING interaction network

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second shell of interactors

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Score

GBP2

Guanylate binding protein 2. (591 aa)

Predicted Functional Partners:

GBP3

0.978

GBP1

0.964

GBP5

0.964

FURIN

0.796

ADD1

0.706

IRF1

0.582

STAT1

0.578

SFN

0.565

ADD3

0.564

PDLIM5

0.515

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADD1	ADD3	ENSPPYP00000016255	ENSPPYP00000003074	Alpha-adducin; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin (By similarity); Belongs to the aldolase class II family. Adducin subfamily.	ADD3 isoform 3.	0.997
ADD1	GBP2	ENSPPYP00000016255	ENSPPYP00000001358	Alpha-adducin; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin (By similarity); Belongs to the aldolase class II family. Adducin subfamily.	Guanylate binding protein 2.	0.706
ADD3	ADD1	ENSPPYP00000003074	ENSPPYP00000016255	ADD3 isoform 3.	Alpha-adducin; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin (By similarity); Belongs to the aldolase class II family. Adducin subfamily.	0.997
ADD3	GBP2	ENSPPYP00000003074	ENSPPYP00000001358	ADD3 isoform 3.	Guanylate binding protein 2.	0.564
FURIN	GBP1	ENSPPYP00000007695	ENSPPYP00000001360	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).	0.598
FURIN	GBP2	ENSPPYP00000007695	ENSPPYP00000001358	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Guanylate binding protein 2.	0.796
FURIN	GBP3	ENSPPYP00000007695	ENSPPYP00000001361	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	GBP3 isoform 2.	0.598
FURIN	GBP5	ENSPPYP00000007695	ENSPPYP00000023860	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	GBP5 isoform 2.	0.875
GBP1	FURIN	ENSPPYP00000001360	ENSPPYP00000007695	Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	0.598
GBP1	GBP2	ENSPPYP00000001360	ENSPPYP00000001358	Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).	Guanylate binding protein 2.	0.964
GBP1	GBP3	ENSPPYP00000001360	ENSPPYP00000001361	Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).	GBP3 isoform 2.	0.991
GBP1	GBP5	ENSPPYP00000001360	ENSPPYP00000023860	Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).	GBP5 isoform 2.	0.924
GBP1	IRF1	ENSPPYP00000001360	ENSPPYP00000017628	Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).	Interferon regulatory factor.	0.607
GBP1	PDLIM5	ENSPPYP00000001360	ENSPPYP00000016679	Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).	PDLIM5 isoform 3.	0.515
GBP1	SFN	ENSPPYP00000001360	ENSPPYP00000001937	Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).	SFN isoform 1; Belongs to the 14-3-3 family.	0.818
GBP1	STAT1	ENSPPYP00000001360	ENSPPYP00000014555	Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).	Signal transducer and activator of transcription.	0.844
GBP2	ADD1	ENSPPYP00000001358	ENSPPYP00000016255	Guanylate binding protein 2.	Alpha-adducin; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin (By similarity); Belongs to the aldolase class II family. Adducin subfamily.	0.706
GBP2	ADD3	ENSPPYP00000001358	ENSPPYP00000003074	Guanylate binding protein 2.	ADD3 isoform 3.	0.564
GBP2	FURIN	ENSPPYP00000001358	ENSPPYP00000007695	Guanylate binding protein 2.	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	0.796
GBP2	GBP1	ENSPPYP00000001358	ENSPPYP00000001360	Guanylate binding protein 2.	Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).	0.964