ENSPPYP00000001359 protein (Pongo abelii) - STRING interaction network

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Score

ENSPPYP00000001359

annotation not available (157 aa)

Predicted Functional Partners:

PTGES2

0.935

PTGES

0.933

PRXL2B

0.928

HPGDS

0.912

HPGD

0.912

PTGS2

0.911

PTGS1

0.911

CBR1

0.910

CBR3

0.910

STIP1

0.907

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBR1	CBR3	ENSPPYP00000012724	ENSPPYP00000012725	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity) [...]	Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.997
CBR1	ENSPPYP00000001359	ENSPPYP00000012724	ENSPPYP00000001359	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity) [...]	annotation not available	0.910
CBR1	HPGD	ENSPPYP00000012724	ENSPPYP00000016993	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity) [...]	15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.907
CBR1	PRXL2B	ENSPPYP00000012724	ENSPPYP00000002288	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity) [...]	Prostamide/prostaglandin F synthase; Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity); Belongs to the peroxiredoxin-like PRXL2 family. Prostamide/prostaglandin F synthase subfamily.	0.902
CBR1	PTGES	ENSPPYP00000012724	ENSPPYP00000022060	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity) [...]	Prostaglandin E synthase.	0.915
CBR1	PTGES2	ENSPPYP00000012724	ENSPPYP00000022012	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity) [...]	Prostaglandin E synthase 2.	0.910
CBR3	CBR1	ENSPPYP00000012725	ENSPPYP00000012724	Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity) [...]	0.997
CBR3	ENSPPYP00000001359	ENSPPYP00000012725	ENSPPYP00000001359	Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	annotation not available	0.910
CBR3	HPGD	ENSPPYP00000012725	ENSPPYP00000016993	Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.907
CBR3	PRXL2B	ENSPPYP00000012725	ENSPPYP00000002288	Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Prostamide/prostaglandin F synthase; Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity); Belongs to the peroxiredoxin-like PRXL2 family. Prostamide/prostaglandin F synthase subfamily.	0.901
CBR3	PTGES	ENSPPYP00000012725	ENSPPYP00000022060	Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Prostaglandin E synthase.	0.915
CBR3	PTGES2	ENSPPYP00000012725	ENSPPYP00000022012	Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Prostaglandin E synthase 2.	0.907
ENSPPYP00000001359	CBR1	ENSPPYP00000001359	ENSPPYP00000012724	annotation not available	Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity) [...]	0.910
ENSPPYP00000001359	CBR3	ENSPPYP00000001359	ENSPPYP00000012725	annotation not available	Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.910
ENSPPYP00000001359	HPGD	ENSPPYP00000001359	ENSPPYP00000016993	annotation not available	15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.912
ENSPPYP00000001359	HPGDS	ENSPPYP00000001359	ENSPPYP00000016678	annotation not available	Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.	0.912
ENSPPYP00000001359	PRXL2B	ENSPPYP00000001359	ENSPPYP00000002288	annotation not available	Prostamide/prostaglandin F synthase; Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity); Belongs to the peroxiredoxin-like PRXL2 family. Prostamide/prostaglandin F synthase subfamily.	0.928
ENSPPYP00000001359	PTGES	ENSPPYP00000001359	ENSPPYP00000022060	annotation not available	Prostaglandin E synthase.	0.933
ENSPPYP00000001359	PTGES2	ENSPPYP00000001359	ENSPPYP00000022012	annotation not available	Prostaglandin E synthase 2.	0.935
ENSPPYP00000001359	PTGS1	ENSPPYP00000001359	ENSPPYP00000021934	annotation not available	PTGS1 isoform 4.	0.911