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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GBP1Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity). (590 aa)    
Predicted Functional Partners:
GBP2
Guanylate binding protein 2.
  
 
0.949
GBP3
GBP3 isoform 2.
  
 
0.922
STAT1
Signal transducer and activator of transcription.
   
 
 0.910
GBP5
GBP5 isoform 2.
  
 
0.825
CXCL10
C-X-C motif chemokine.
   
  
 0.806
IFIT3
Interferon induced protein with tetratricopeptide repeats 3.
   
  
 0.745
TAP1
Transporter 1, ATP binding cassette subfamily B member.
   
 
 0.694
IFIH1
IFIH1 isoform 1.
   
 
 0.682
IFIT2
IFIT2 isoform 1.
   
  
 0.677
IFI44
IFI44 isoform 2.
   
  
 0.673
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.