STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CR201_G0055545RPS2 isoform 6; Belongs to the universal ribosomal protein uS5 family. (245 aa)    
Predicted Functional Partners:
RPS3
40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...]
  
 0.973
RPS13
Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.
   
 0.969
RPS11
RPS11 isoform 3; Belongs to the universal ribosomal protein uS17 family.
  
 0.969
RPS9
Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family.
  
 0.968
RPS19
40S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family.
   
 0.967
RPS29
40S ribosomal protein S29.
  
 0.964
CR201_G0031384
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.960
FAU
Ubiquitin-like protein FUBI.
   
 0.960
RPS15
40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
  
 0.957
RPS3A
40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.
   
 0.957
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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