Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLCA4CLCA4 isoform 1. (913 aa)    
Predicted Functional Partners:
CLCA2
CLCA2 isoform 1.
  
  
 
0.928
CLCA1
CLCA1 isoform 1.
  
 
 
0.922
ANO2
Anoctamin.
      
 0.732
ANO1
Anoctamin.
      
 0.724
LIX1
Limb and CNS expressed 1.
   
  
 0.704
CWC25
CWC25 spliceosome associated protein homolog.
   
    0.641
FAM20B
FAM20B isoform 2.
   
 
  0.617
C1orf109
Chromosome 1 open reading frame 109.
   
    0.614
SLCO1A2
Solute carrier organic anion transporter family member.
   
    0.611
UGT3A1
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 
 0.608
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (8%) [HD]