MCOLN2 protein (Pongo abelii) - STRING interaction network

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[Homology]

Score

MCOLN2

MCOLN2 isoform 1. (532 aa)

Predicted Functional Partners:

MCOLN3

0.979

P2RY6

0.568

PDF

0.552

TTC17

0.543

VSIG10

0.521

TRPA1

0.505

TRPM2

0.496

TFEB

0.490

LYPLAL1

0.471

ATP6V1H

0.467

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V1H	MCOLN2	ENSPPYP00000020844	ENSPPYP00000001389	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	MCOLN2 isoform 1.	0.467
ATP6V1H	MCOLN3	ENSPPYP00000020844	ENSPPYP00000001388	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	MCOLN3 isoform 4.	0.588
ATP6V1H	TFEB	ENSPPYP00000020844	ENSPPYP00000018565	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	TFEB isoform 3.	0.630
LYPLAL1	MCOLN2	ENSPPYP00000000218	ENSPPYP00000001389	Lysophospholipase-like protein 1; Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site (By similarity); Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.	MCOLN2 isoform 1.	0.471
LYPLAL1	TTC17	ENSPPYP00000000218	ENSPPYP00000003838	Lysophospholipase-like protein 1; Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site (By similarity); Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.	TTC17 isoform 2.	0.514
LYPLAL1	VSIG10	ENSPPYP00000000218	ENSPPYP00000005711	Lysophospholipase-like protein 1; Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site (By similarity); Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.	VSIG10 isoform 6.	0.517
MCOLN2	ATP6V1H	ENSPPYP00000001389	ENSPPYP00000020844	MCOLN2 isoform 1.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.467
MCOLN2	LYPLAL1	ENSPPYP00000001389	ENSPPYP00000000218	MCOLN2 isoform 1.	Lysophospholipase-like protein 1; Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site (By similarity); Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.	0.471
MCOLN2	MCOLN3	ENSPPYP00000001389	ENSPPYP00000001388	MCOLN2 isoform 1.	MCOLN3 isoform 4.	0.979
MCOLN2	P2RY6	ENSPPYP00000001389	ENSPPYP00000004182	MCOLN2 isoform 1.	P2RY6 isoform 1.	0.568
MCOLN2	PDF	ENSPPYP00000001389	ENSPPYP00000008469	MCOLN2 isoform 1.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.	0.552
MCOLN2	TFEB	ENSPPYP00000001389	ENSPPYP00000018565	MCOLN2 isoform 1.	TFEB isoform 3.	0.490
MCOLN2	TRPA1	ENSPPYP00000001389	ENSPPYP00000020939	MCOLN2 isoform 1.	TRPA1 isoform 1; Belongs to the transient receptor (TC 1.A.4) family.	0.505
MCOLN2	TRPM2	ENSPPYP00000001389	ENSPPYP00000012823	MCOLN2 isoform 1.	TRPM2 isoform 3.	0.496
MCOLN2	TTC17	ENSPPYP00000001389	ENSPPYP00000003838	MCOLN2 isoform 1.	TTC17 isoform 2.	0.543
MCOLN2	VSIG10	ENSPPYP00000001389	ENSPPYP00000005711	MCOLN2 isoform 1.	VSIG10 isoform 6.	0.521
MCOLN3	ATP6V1H	ENSPPYP00000001388	ENSPPYP00000020844	MCOLN3 isoform 4.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.588
MCOLN3	MCOLN2	ENSPPYP00000001388	ENSPPYP00000001389	MCOLN3 isoform 4.	MCOLN2 isoform 1.	0.979
MCOLN3	TFEB	ENSPPYP00000001388	ENSPPYP00000018565	MCOLN3 isoform 4.	TFEB isoform 3.	0.634
MCOLN3	TRPA1	ENSPPYP00000001388	ENSPPYP00000020939	MCOLN3 isoform 4.	TRPA1 isoform 1; Belongs to the transient receptor (TC 1.A.4) family.	0.505