ADGRL2 protein (Pongo abelii) - STRING interaction network

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Score

ADGRL2

ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family. (1220 aa)

Predicted Functional Partners:

LRMDA

0.861

CLVS1

0.822

IGSF21

0.778

VPS13C

0.775

GNB5

0.752

GNB1

0.745

GNB3

0.745

FRMD6

0.745

GNB2

0.745

KCNH7

0.733

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRL2	CLVS1	ENSPPYP00000001403	ENSPPYP00000020881	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).	0.822
ADGRL2	FRMD6	ENSPPYP00000001403	ENSPPYP00000006604	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	FERM domain containing 6.	0.745
ADGRL2	GNB1	ENSPPYP00000001403	ENSPPYP00000002307	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.745
ADGRL2	GNB2	ENSPPYP00000001403	ENSPPYP00000019528	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	GNB2 isoform 1.	0.745
ADGRL2	GNB3	ENSPPYP00000001403	ENSPPYP00000004790	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	G protein subunit beta 3.	0.745
ADGRL2	GNB5	ENSPPYP00000001403	ENSPPYP00000007348	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.752
ADGRL2	IGSF21	ENSPPYP00000001403	ENSPPYP00000002095	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	IGSF21 isoform 1.	0.778
ADGRL2	KCNH7	ENSPPYP00000001403	ENSPPYP00000014385	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	KCNH7 isoform 2.	0.733
ADGRL2	LRMDA	ENSPPYP00000001403	ENSPPYP00000002686	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	Leucine rich melanocyte differentiation associated.	0.861
ADGRL2	VPS13C	ENSPPYP00000001403	ENSPPYP00000007404	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	VPS13C isoform 1.	0.775
CLVS1	ADGRL2	ENSPPYP00000020881	ENSPPYP00000001403	Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	0.822
CLVS1	IGSF21	ENSPPYP00000020881	ENSPPYP00000002095	Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).	IGSF21 isoform 1.	0.814
CLVS1	KCNH7	ENSPPYP00000020881	ENSPPYP00000014385	Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).	KCNH7 isoform 2.	0.774
CLVS1	LRMDA	ENSPPYP00000020881	ENSPPYP00000002686	Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).	Leucine rich melanocyte differentiation associated.	0.827
CLVS1	VPS13C	ENSPPYP00000020881	ENSPPYP00000007404	Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity).	VPS13C isoform 1.	0.812
FRMD6	ADGRL2	ENSPPYP00000006604	ENSPPYP00000001403	FERM domain containing 6.	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	0.745
FRMD6	GNB1	ENSPPYP00000006604	ENSPPYP00000002307	FERM domain containing 6.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.736
FRMD6	GNB2	ENSPPYP00000006604	ENSPPYP00000019528	FERM domain containing 6.	GNB2 isoform 1.	0.626
FRMD6	GNB3	ENSPPYP00000006604	ENSPPYP00000004790	FERM domain containing 6.	G protein subunit beta 3.	0.489
GNB1	ADGRL2	ENSPPYP00000002307	ENSPPYP00000001403	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	ADGRL2 isoform 14; Belongs to the G-protein coupled receptor 2 family.	0.745