Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CR201_G0008700ADGRL4 isoform 1; Belongs to the G-protein coupled receptor 2 family. (513 aa)    
Predicted Functional Partners:
EMCN
Endomucin; Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
   
  
 0.779
HSD17B14
Hydroxysteroid 17-beta dehydrogenase 14.
      
 0.659
SCT
SCT isoform 1.
      
 0.617
CR201_G0003959
MYCT1 isoform 2.
   
  
 0.601
SLC29A1
SLC29A1 isoform 1.
    
 
 0.552
CYYR1
CYYR1 isoform 1.
   
    0.537
CD63
Tetraspanin.
    
   0.528
MIGA1
MIGA1 isoform 1.
      
 0.487
ZZZ3
ZZZ3 isoform 2.
      
 0.486
MOSPD1
Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to- mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation.
    
 
 0.472
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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