Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GIPC2GIPC2 isoform 2. (316 aa)    
Predicted Functional Partners:
APPL1
APPL1 isoform 1.
   
 
 0.802
SH3BP4
SH3BP4 isoform 1.
   
 
 0.798
NTRK1
Tyrosine-protein kinase receptor.
   
 
 0.772
APPL2
APPL2 isoform 1.
   
 
 0.745
MYO6
MYO6 isoform 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.737
GIPC1
GIPC PDZ domain containing family member 1.
    
   0.711
SP100
SP100 isoform 3.
    
   0.677
FZD3
Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 
 0.634
TGFBR3
TGFBR3 isoform 1.
    
 0.537
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
     
  0.514
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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