Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FUBP1FUBP1 isoform 8. (662 aa)    
Predicted Functional Partners:
KHSRP
KHSRP isoform 3.
   
   0.963
ENSPPYP00000021481
annotation not available
   
   0.963
PUF60
Poly(U)-binding-splicing factor PUF60; DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Is also involved in pre-mRNA splicing. Promotes splicing of an intron with weak 3'-splice si [...]
   
 
 0.936
FUBP3
Far upstream element binding protein 3.
   
   0.935
HNRNPM
Heterogeneous nuclear ribonucleoprotein M.
   
 
 0.853
BRDT
BRDT isoform 3.
   
 
 0.848
AIMP2
Aminoacyl tRNA synthetase complex interacting multifunctional protein 2.
    
 
 0.796
TK1
Thymidine kinase.
      
 0.792
HNRNPR
HNRNPR isoform 2.
   
 
 0.775
PCBP1
Poly(rC) binding protein 1.
   
 
 0.761
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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