Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZZZ3ZZZ3 isoform 2. (903 aa)    
Predicted Functional Partners:
TADA3
Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).
    
 0.992
SGF29
SAGA complex associated factor 29.
    
 0.991
KAT14
Lysine acetyltransferase 14.
   
 0.991
MBIP
MBIP isoform 1.
    
 0.990
TADA2A
Transcriptional adapter.
  
 
 0.986
YEATS2
YEATS domain containing 2.
   
 0.983
KAT2B
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
    
 0.975
DR1
Down-regulator of transcription 1.
    
 0.974
WDR5B
WD repeat-containing protein 5B; May function as a substrate receptor for CUL4-DDB1 ubiquitin E3 ligase complex; Belongs to the WD repeat WDR5/wds family.
    
 0.951
WDR5
WDR5 isoform 1.
    
 0.898
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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