Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RPE65Retinoid isomerohydrolase RPE65. (533 aa)    
Predicted Functional Partners:
LRAT
LRAT isoform 2.
     
 0.972
RDH5
11-cis retinol dehydrogenase.
     
 0.946
RDH11
Retinol dehydrogenase 11 precursor.
     
 0.928
RDH10
Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.928
DGAT1
O-acyltransferase.
   
 
 0.919
PNPLA4
PNPLA4 isoform 1.
     
 0.905
AWAT2
Acyl-CoA wax alcohol acyltransferase 2.
   
 
 0.904
MERTK
MERTK isoform 2.
     
 0.736
RDH12
Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.688
AIPL1
Aryl hydrocarbon receptor interacting protein like 1.
      
 0.653
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.