SERBP1 protein (Pongo abelii) - STRING interaction network

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Score

SERBP1

SERBP1 isoform 3. (382 aa)

Predicted Functional Partners:

RPS3A

0.959

RPS12

0.957

RPL7A

0.954

RPS3

0.952

RPS20

0.925

RPS15

0.923

NCL

0.918

RPS5

0.909

RPL4

0.908

RPS19

0.906

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NCL	RPL4	ENSPPYP00000014829	ENSPPYP00000015792	Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity).	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	0.745
NCL	RPL7A	ENSPPYP00000014829	ENSPPYP00000022127	Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity).	RPL7A isoform 3.	0.555
NCL	RPS12	ENSPPYP00000014829	ENSPPYP00000019058	Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity).	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.	0.495
NCL	RPS15	ENSPPYP00000014829	ENSPPYP00000010457	Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity).	40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.	0.447
NCL	RPS19	ENSPPYP00000014829	ENSPPYP00000011224	Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity).	40S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family.	0.583
NCL	RPS20	ENSPPYP00000014829	ENSPPYP00000020858	Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity).	40S ribosomal protein S20.	0.471
NCL	RPS3	ENSPPYP00000014829	ENSPPYP00000004215	Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity).	40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...]	0.608
NCL	RPS3A	ENSPPYP00000014829	ENSPPYP00000023498	Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity).	40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.	0.636
NCL	RPS5	ENSPPYP00000014829	ENSPPYP00000024669	Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity).	RPS5 isoform 1; Belongs to the universal ribosomal protein uS7 family.	0.594
NCL	SERBP1	ENSPPYP00000014829	ENSPPYP00000001462	Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity).	SERBP1 isoform 3.	0.918
RPL4	NCL	ENSPPYP00000015792	ENSPPYP00000014829	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity).	0.745
RPL4	RPL7A	ENSPPYP00000015792	ENSPPYP00000022127	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	RPL7A isoform 3.	0.982
RPL4	RPS12	ENSPPYP00000015792	ENSPPYP00000019058	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.	0.973
RPL4	RPS15	ENSPPYP00000015792	ENSPPYP00000010457	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.	0.989
RPL4	RPS19	ENSPPYP00000015792	ENSPPYP00000011224	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	40S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family.	0.980
RPL4	RPS20	ENSPPYP00000015792	ENSPPYP00000020858	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	40S ribosomal protein S20.	0.998
RPL4	RPS3	ENSPPYP00000015792	ENSPPYP00000004215	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...]	0.994
RPL4	RPS3A	ENSPPYP00000015792	ENSPPYP00000023498	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.	0.993
RPL4	RPS5	ENSPPYP00000015792	ENSPPYP00000024669	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	RPS5 isoform 1; Belongs to the universal ribosomal protein uS7 family.	0.992
RPL4	SERBP1	ENSPPYP00000015792	ENSPPYP00000001462	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	SERBP1 isoform 3.	0.908